Delayed wound healing in leukocyte adhesion deficiency type 1.
نویسندگان
چکیده
*KURAに登録されているコンテンツの利用については,著作権法に規定されている私的使用や引用などの範囲内で行ってください。 *著作権法に規定されている私的使用や引用などの範囲を超える利用を行う場合には,著作権者の許諾を得てください。ただし,著作権者 から著作権等管理事業者(学術著作権協会,日本著作出版権管理システムなど)に権利委託されているコンテンツの利用手続については ,各著作権等管理事業者に確認してください。 Title Delayed Wound Healing in Leukocyte Adhesion Deficiency Type 1 Author(s) Wada, Taizo; Tone, Yumi; Shibata, Fumie; Toma, Tomoko; Yachie, Akihiro Citation Journal of Pediatrics, 158(2): 342 Issue Date 2011-02 Type Journal Article Text version author URL http://hdl.handle.net/2297/25262 Right
منابع مشابه
Leukocyte adhesion deficiency type I--a focus on oral disease in a young child.
This paper presents a case of the moderate form of Leukocyte adhesion deficiency type 1 (LAD-1) in a 4 year-old boy. LAD-1 is a rare, inherited immunodeficiency that affects 1 in 1 million people yearly. Affected patients are susceptible to recurrent bacterial and fungal infections, impaired pus formation and delayed wound healing. In the oral clinical finding, more important is a generalized p...
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The hallmarks of leukocyte adhesion deficiency (LAD) are defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections. These molecular and clinical manifestations result from an impaired step in the inflammatory process, namely, the emigration of leukocytes from the blood vessels to sites of infection, which requires adhesion of leukocytes to the endothelium. Over las...
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Leukocyte adhesion deficiency (LAD) is characterized by the inability of leukocytes, in particular neutrophilic granulocytes, to emigrate from the bloodstream towards sites of inflammation. Infectious foci are nonpurulent and may eventually become necrotic because of abnormal wound healing. LAD-1 is characterized by the absence of the beta2 integrins (CD11/CD18) on leukocytes. When expression i...
متن کاملPeriodontal manifestation of leukocyte adhesion deficiency type I.
BACKGROUND Leukocyte adhesion deficiency type I (LAD-I) is an autosomal recessive immunodeficiency disorder characterized by defects in the integrin receptors of white blood cells that lead to impaired adhesion and chemotaxis. Affected patients are susceptible to recurrent bacterial and fungal infections, impaired pus formation, delayed wound healing, and periodontitis. METHODS A case of gene...
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ورودعنوان ژورنال:
- The Journal of pediatrics
دوره 158 2 شماره
صفحات -
تاریخ انتشار 2011